Identify Subjects / Request Data

Enterprise-wide data services are available to help Mass General Brigham investigators and research groups expedite the process of obtaining data for analysis or to gauge study feasibility. Repositories of clinical samples and data, as well as public data sets, are accessible to researchers through the tools and processes outlined below.

A new initiative, the Mass General Brigham Big Data Commons, enables Big Data to be integrated with the RPDR and tighter integration of the RPDR with Epic. The specific areas of focus of the Big Data Commons are to create a Research Patient Portal for direct patient engagement in Epic, creating a distributed query system to allow more types of Partners Big Data to be integrated and become discoverable by researchers, and specific integration platforms such as the Biobank Portal which serve to researchers new forms of Big Data in easily consumable forms. 

Research Data Dictionary in Collibra

Data Dictionaries for RISC Data Repositories

Research Patient Data Registry

Research Patient Data Registry (RPDR)

RPDR Daily Query Tool

The RPDR has a new Daily Query Tool where users can query source systems which are updated in the RPDR on a daily basis.

RPDR Daily Query Tool
The RPDR has a new Daily Query Tool which can be accessed through the Partners Application Menu or the RPDR homepage (

This new functionality, allows users to query source systems that are updated in the RPDR on a daily basis. These include Encounter Detail, Demographic Detail, Laboratory Tests, Radiology Tests, Providers, Specimens, Transfusion Services,  Biobank Patient Consents and perhaps the most powerful is the Notes Search (EPIC + LMR Ambulatory notes and Clinical Reports). Using the Notes Search in the Daily Query tool allows users to search for terms contained in notes without having to wait for delayed coded information.

 In addition to having more patients available, the daily query tool is helpful for finding time-sensitive patients for enrollment in studies and clinical trials.

 Identified detailed data (Demographic and Identifying Patient Information) can be requested through the Daily Query Tool.

*Note: (this link is internal only and requires Internet Explorer; you must be logged on to a Mass General Brigham workstation or connected to the Mass General Brigham network via VPN)*

Biobank Portal

Biobank Portal

Accrual to Clinical Trials (ACT) Network

The ACT Network is a real-time platform allowing researchers to explore and validate feasibility for clinical studies from their desktops.

mi2B2 Medical Image Access Tool

mi2B2 Medical Image Access Tool

mi2b2 - Medical Image Access Tool

The Medical Imaging Informatics Bench to Bedside (mi2b2) workbench serves as a secure bridge between a researcher and the Mass General Brigham PACS systems, which aims to:

  • Facilitate searching for, reviewing, and accessing clinically acquired images that are stored in several PACS (Picture Archive and Communication System) systems that serve the Mass General Brigham institutions
  • Enable researchers to extend the use of the Research Patient Data Registry (RPDR) to access clinical images on patients of interest for enhanced research studies, with proper IRB approval
  • Enable efficient retrieval of medical images (DICOM format) for lists of patients generated from research, teaching, and clinical activities in keeping with all regulatory guidelines
  • Provide access to only patient images authorized by approved IRBs and provide audit trails for HIPAA compliance.

If using the RPDR Query tool and the RPDR Data Acquisition Engine (Image Request Wizard), a  user can obtain aggregate numbers of patients with user-defined characteristics based on a query or upload a pre-defined list of Medical Record Numbers and then receive more detailed medical information about the queried patient cohort. Either way, the user is provided with a personalized mi2b2 workbench, directly configured to include the queried cohort information. It is delivered in a folder along with the encrypted RPDR data results. For instructions on how to use the RPDR to request mi2b2 workbench, please visit: ( ->Help -> Request Images Help.

 Detailed tutorial support for new users of the mi2b2 software is found at

Shared Data Sets

The IDEA Platform hosts public data sets that research teams at Mass General Brigham can access using standard data analysis tools.

Epic/Mass General Brigham eCare Reporting Workbench for research

For research data queries, Investigators should use the RPDR, the Epic/Mass General Brigham eCare Reporting Workbench should not be used.

Use of the Epic/Mass General Brigham eCare Reporting Workbench for research is medical records research.

REMINDER: The Epic/Mass General Brigham eCare Reporting Workbench tool is for use in clinical care.

For research data queries, Investigators should use the Research Patient Data Registry (RPDR); the Epic/Mass General Brigam eCare Reporting Workbench tool should not be used.

If RPDR is insufficient for your research, you may use the Epic/Mass General Brigham eCare Reporting Workbench if:

  • you have IRB approval AND
  • use is in accordance with specific restrictions as outlined in the FAQs.

Use of medical records and protected health information (PHI) for research must be compliant with the HIPAA Privacy Rule, the Common Rule, and other laws that regulate patient and study subject privacy, in addition to Mass General Brigham policies on encryption and Information Security.

Thank you,
Paul J. Anderson, MD, PhD, Chief Academic Officer, Brigham and Women’s Hospital
O’Neil Britton, MD, CHIO, Partners HealthCare
Shelly Greenfield, MD, MPH, Chief Academic Officer, McLean Hospital
Jigar Kadakia, Chief Information Security and Privacy Officer, Partners HealthCare
Anne Klibanski, MD, Chief Academic Officer, Partners HealthCare
Janet (Jodi) Larson, MD, Acting Associate Chief Medical Officer, Newton Wellesley Hospital
Gregg S. Meyer, MD, Chief Clinical Officer, Partners HealthCare
Harry W. Orf, PhD, Senior Vice President for Research, Massachusetts General Hospital
Kerry Ressler, MD, PhD, Chief Scientific Officer, McLean Hospital
Ross Zafonte, DO, Senior Vice President of Medical Affairs, Research and Education, Spaulding Rehabilitation Network



The Care Cube Limited Exam Extraction Service is a service where researchers may request up to 1,000 studies to be extracted and stored in a temporary storage location that has access control by a PAS group.  The expected extraction time is 5 days once the completed request is submitted and assigned.

Request Process:

The requestor will need to complete the Radiology Imaging Request form and supply a csv or xls file with the following minimum information:

  • Patient MRN,
  • Accession Number; and
  • Site where the images were obtained.

Once the data is compiled, email the Request form and csv or xls file to MGB Radiology Imaging Requests where it will be assigned.  

When the request is fulfilled, the requester will be notified via email with instructions on how to access the files.  Files may be stored in the temporary, free location for up to 180 day.  If the images are to be kept >180 days, the research team must move the images to their own permanent storage location. Fee for service storage options may be found on the ERIS website.

*Please note, a Partners Authorization System (PAS) group is required for granting access to the directory where the data will be stored on a temporary basis.