Launched in 2020, the Analytics Enclave, "Enclave", is a highly secure, privacy-aware, data ecosystem equipped with self-service AI, machine learning, and data science tools that facilitate on-demand data analysis at the project-, program-, or institution-level.

The controlled and protected environment offers authorized users a dedicated, centralized, scalable, and customizable workspace for collaboration on highly confidential or sensitive data with predictable timeframe for completing planned or exploratory analyses.

The Enclave supports cross-institutional collaboration (for example: MGB research community and external clinical industry partners) on MGB data or curated data marts. At present, the Enclave has several COVID-19 data marts and project-specific databases.

As of May 1, 2024, the Enclave hosts a total of 151 active research projects and 215 members of the scientific community.

Analytics Enclave Offerings

The Enclave has a baseline offering of widely used data science tools

The Enclave is equipped with an array of software programs and applications. These computational resources and data sources are updated regularly.

The Enclave-hosted repositories include CRAN, Bioconductor, PyPI, and more.

Windows 10 Enclave Virtual Desktop

Documentation and Statistical Analysis Tools Programming Tools Development Platforms









Loupe Browser



Microsoft Office Suite (Word/Excel/PowerPoint)

Jupyter Notebook


RStudio Package Manager (RSPM) - Beta





JAVA Runtime Environment

Java SE Development Kit

JFrog Artifactory

IntelliJ IDEA Community Edition

PyCharm Community

Visual Studio Code

MS SQL Server

Linux Enclave Virtual Desktop With GPU

Documentation and Statistical Analysis Tools Programming Tools Development Platforms




LibreOffice Suite

Cell Ranger





Visual Studio Code DBeaver


Standard Resources Allocated Per User
  Windows 10 VDI Linux VDI
CPU (Intel Xeon Platinum @2.4GHz) 4 vCPU 4 CPU
RAM 16 GB 16 GB
Local Storage (NVMe) 70 GB 100 GB
Standard Resources Allocated Per Project

Network Attached Storage 

(Note: Additional storage capacity can be provisioned as needed; subject to justification and approval)

100 - 500 GB

Object Storage (S3)

(Note: Provisioned upon request)

1 TB

Data Sources  

Complete & submit the request form to access these repositories
Research Project-Specific Data in Enclave Workspace
COVID-19 Data Mart
Detailed Data Files of COVID-19 Data
COVID-19 Vaccine Registry
COVID-19 Vaccine Self-Reported Symptoms Database
ECG Data Files (static data)
Complete PDSR Curated Data Set
Accessing the Analytics Enclave

Access to the Enclave involves a strict project-specific approval process for each applicant

Access to the Enclave is granted upon completion and submission of the Access Request Form

On approval, the applicant's Enclave Workspace is provisioned per project. They can access their dedicated Enclave Virtual Desktop(s) by logging in with their Mass General Brigham username and password via the VMware Horizon Virtual Desktop Infrastructure (VDI).

1. Plan ahead
  • Prepare or organize the data you will bring into the  Enclave.
  • Carefully read the requirements for accessing the COVID-19 data. For example, your IRB-approved protocol should describe the proposed use of the COVID-specific identifiable data if access to the the COVID data marts is requested
  • Review the information at Research Data Dictionaries In Collibra to ascertain the availability of data in support of your research

Note: No cost to MGB-affiliated applicants

2. Complete & submit the online form
  • Submit the online access request form
  • The required information include:
    • Project principal investigator's contact information
    • Project information (e.g. title, IRB #, expiration date)
    • Specify whether or not access to the RISC-owned or managed databases is requested
    • Check off database(s) for which access is requested
    • Specify if only project generated or acquired data will be analyzed
  • Follow these instructions.
3. Application review
  • Application is reviewed for completeness (e.g. dates /duration of access and use of the Enclave and respective databases, confirmation the applicant is a member of the research project)
  • Project’s principal investigator approves project member’s access
4. Enclave Workspace provisioning & notification of access approval
  • Analytics Enclave Workspace is provisioned.
  • Information on the Enclave Platform access and use requirements is sent to the applicant via email
5. Access the Enclave Virtual Desktop Computer
  • Access the workspace remotely via VMware Horizon Virtual Desktop Infrastructure (VDI) - [Enclave Virtual Desktop (EVD)]
  • Access the readily-available data analytics tools
  • Use the project-specific P: Drive for file/data sharing and collaboration
  • Leverage the technical support for the duration of the project
Analytics Enclave Support

Leverage technical support to enhance your overall experience with the Analytics Enclave

Do you need assistance with the Analytics Enclave? We Got You

In line with the ERIS Service Level Agreement (SLA), the Analytics Enclave team offers support during working hours, from 9:00 to 17:00 on Monday to Friday, on working days. More information on the ERIS SLA is available here.

The support offered includes but is not limited to:

  1. Onboarding new users.
  2. Troubleshooting and addressing technical issues or queries.
  3. Scheduled support sessions.
  4. Managing requests for additional functionality or feature, or modification to existing features.